Theme: Individual to Populations

Disentangling Individual from Population Health

ABOUT

The primary goal of this theme is to encourage studies that bridge the gap between the unique responses of individuals (precision medicine approaches) and population-level studies (epidemiological-scale approaches). In recent years, modern health care delivery has become more and more "personalized" but efforts to tailor disease prevention or understand individual environmental sensitivities have not been prioritized. The Center has made the Individuals to Populations research theme in an effort to initiate collaborations among TiCER scientists focused on understanding the linkages between specific exposures and adverse health responses or disease development and how unique disease mechanisms are modulated by inter-individual genetic differences.

RESEARCH FOCI:

    • Understanding the relationship between individual and population responses is a novel research concept for many TiCER scientists. However, several new recruits have extensive expertise in this area and will pioneer studies that bridge homogenous models with heterogenous population models that more accurately represent populations in reality. 
    • Current studies are investigating population diversity of responses to environmental exposure of trichloroethylene, arsenic, and lead. These studies will act as paradigms for scientists expanding into this new area of research.
    • Future studies will investigate inter-individual variation in response to:
      • air pollutants
      • microbiota
      • plant metabolites

Research THEME LEADER

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Dr. Ivan Rusyn is a professor in A&M's Department of Veterinary Integrative Biosciences. He has an extensive record translating exposure studies from homogenous genetic backgrounds to heterogenous backgrounds more representative of human populations. His research focuses primarily on understanding why certain chemicals cause cancer or organ damage in rodent models and determining if humans are at risk from similar exposure.

VISIT LAB

THeme Members

Ivan Rusyn
Principal Investigator
Integrated Health Sciences Facility Core

Individuals to Populations
Natalie Johnson
Co Investigator
Integrated Health Sciences Facility Core

Individuals to Populations
Benjamin Morpugo
Co-Investigator
Integrated Health Science Facility Core

Individuals to Populations
Itza Mendoza-Sanchez
Assistant Professor
Integrated Health Science Facility Core

Individuals to Populations
Andrew Hillhouse
Co-Investigator
Chem Science Facility Core

Individuals to Populations
Candice Brinkmeyer-Langford
Member

Individuals to Populations
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Funding Opportunities

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